Peer-Reviewed Evidence. Real-World Results.
- See why leading clinics trust Nanodropper to improve outcomes and reduce waste
60–80% of Waste Eliminated with Precise Microdrops
Equivalent or Superior Efficacy
Lower Side Effects & Reduced Early Bottle Exhaustion
Data summary sheet
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Peer-reviewed publications
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Historical data
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Why micro-volume delivery?
Studies from the 1980’s have demonstrated the potential benefits of micro-volume delivery to maximize efficacy and minimize side effects and systemic absorption. Dr. Allisa Song, Dr. Jennifer Steger, and Dr. Alan Robin published on the anatomical and physiologic constraints of the eye to explain the outcomes we see with micro-volume delivery of topical ophthalmics.
Core Studies
Peer-Reviewed Publications of Prospective Randomized-Controlled Clinical Trials with Nanodropper Adaptor
12-week Crossover Study in Stable Glaucoma Patients
Real-world efficacy, safety, and usability of a microvolume eyedrop delivery device in glaucoma: prospective randomized crossover trial
Jennifer S Steger, José E Capó-Aponte, Alexandra Papp, Alexandra J Schulte, Eric P Grewal, Allisa J Song, Elizabeth Colantuoni, Jared C Kelstrom, Alan L Robin
Key Conclusions
- 9.6% Superior IOP-lowering of microdrops
- 67% reduction in adverse events
- 80% reduction in early bottle exhaustion
Efficacy and Safety of Timolol 0.5% Microdrops
An Evaluation of the Efficacy and Safety of Timolol Maleate 0.5% Microdrops Administered with the Nanodropper
Jennifer S Steger, Indira Durai, Annamalai Odayappan, Ramalakshmi Raman, Talla Sruthi, Allisa J Song, George Puthuran, Rengaraj Venkatesh, Elizabeth Colantuoni, Alan L Robin
Key Conclusions
- No between-group difference in IOP at any time point
- 60% reduction in heart rate change from baseline
Pupillary Dilation in Pediatric Eyes with Microdrops
Randomized Trial to Evaluate the Efficacy of the Nanodropper Device for Pupillary Dilation and Cycloplegia in Children
Charis B Hoppe, Sean Yonamine, Brandon W Kao, Marcus L Turner, Yvonne Ou, Ying Han, Jeremy D Keenan, Julius T Oatts
Key Conclusions
- Non-inferiority of mydriatic microdrops established for maximum pupil diameter
Dilation Studies in Pediatric & Adult Populations
OHT & Glaucoma Studies
Benchtop Study on Volume Reduction & Precision
List of Active Clinical Trials
Interested in collaborating with us on the next study?
Listen to peers discuss the clinical benefits
"Patients are coming back and using it. And I'm still getting good pressure lowering...Less is more. It's exciting to have this tool that is pretty easy to get, and now we have it as a product in our office."
Dr. Okeke, MD, MSCE